First off, speculation is no longer necessary: Suda 51's latest, Killer Is Dead, is definitely coming to America thanks to XSEED, as previously assumed.
The game will arrive sometime during the summer of 2013, for both the Xbox 360 and PS3. But XSEED has also revealed that they're bring bringing over a bunch of other games this year as well. Five in total, covering practically every single platform one can think of.
In addition to Killer Is Dead, you have Rune Factory 4 for the 3DS. It's the first time the simulation/role-playing franchise has been released on the three dimensionally inclined Nintendo handheld, and will also see a summer release.
Next there's Valhalla Knights 3, which is actually the fourth game in the series. Parts 1 and 2 were for the PlayStation Portable, whereas the Eldar Saga spin-off came out for the Wii. This latest installment is for the Vita and is due for arrival in the fall of this year.
Meanwhile, XSEED is showing Vita even more TLC in the form of Ys: Memories of Celceta, which is described as an extensive re-imagining of, as well as pseudo-sequel to Ys IV, the one installment of the long running RPG to never make it to America. It too is coming in the fall of 2013.
Speaking of Ys, yet another re-release/remake/revamp of Ys I & II is being prepped, this time for the PC, via Steam. In addition to the two originals, included is Ancient Ys Vanished: Omen and Ancient Ys Vanished: The Final Chapter. Those who want to see what Ys is all about have the least amount of time to wait; the package arrives later this month.