#2 Grand Theft Auto V
Grand Theft Auto V, like every other Rockstar Game, will be "done when its done" but we've a pretty good feeling it'll be released in 2012. Given the state and the quality of its recently revealed teaser trailer, and the fact that Grand Theft Auto V is being developed for the current generation Xbox 360 and PlayStation 3, there's little doubt it'll make it out next year before any new consoles are announced, much less released.
Grand Theft Auto V will take players back to Los Santos, which appears to be a sort of retcon of San Andreas, featured in the earlier GTA title of the same name. Designed as an analog of Los Angeles, players take on the role of former criminal, whose attempts to turn away from his life of crime lead him back to where he started. The old adage proves true—once a thief, always a thief.
Like Red Dead Redemption and Grand Theft Auto IV before it, GTA V has serious undertones, with a story that hinges greatly upon the current economic inequality facing most citizens of the United States—or the 99%. It goes without saying that Rockstar's undertaking will be their greatest one yet.