Top 10 Worst Plagues In Gaming History

9. Las Plagas – Resident Evil 4

Las Plagas is a parasitic organism that affects a variety of hosts, including humans and animals, that induces a hive-like mentality into the minds of the afflicted subjects. Afflicted individuals then display extreme hostility towards any uninfected creatures. 

However unlike most zombie type viruses, the Las Plagas virus does not debilitate a human by affecting their fine motor skills, and even allows them to manipulate complicated weapons. Much like ants and bees, those afflicted follow the orders of a ‘Queen’ parasite.