Blizzard's wasting no effort in building up the hype and anticipation for Diablo III, and it's managed to do so (whether intentionally or not) by releasing a launch day preparation guide which covers every foreseeable aspect of getting the game up and running when it's launched on May 15.
The guide covers early installs for digital downloaders, the exact time of release for each region, and possible errors that players may experience upon the game's launch. You'll also have to set up a BattleTag (which is something you can do right now) to play the game.
According to the guide, digital downloaders can unlock the game's installer on May 14—a day before everyone else—just so you can get the game up and running the moment it's launched.
You can read the entire guide here. Try not to wet yourself in anticipation.