In a post by dgonreddit on the Microsoft subreddit, a user shared how the recent Windows 8.1 update makes it difficult for most games to read raw mouse data which makes them unplayable. It is clear that it is not a isolated issues as other people have confirmed in the comments that this appears to be a widespread issue.
"Just a warning to everyone who games on their PC and has Windows 8 installed: do not upgrade to WINDOWS 8.1. Something about Window's relationship with your mouse has been altered (specifically, the Multi DPI improvement for multiple monitors) and this causes those games that don't read raw mouse data to become close-to unplayable.
I stumbled upon this issue because it affects two (!) games I'm trying to play through right now, Deus Ex: Human Revolution and STALKER: Call of Prypiat. Hacking in Human Revolution is particularly unplayable with this issue. Reading around the internet for support, apparently Call of Duty is affected as well.
Just thought I'd release a friendly warning! If anyone has any links to work-arounds, I'd appreciate it just as much!"
For those looking for a more detailed and technical explanation for the issue, user Mark Cranness explained it in a lengthy yet informative comment. He also offered a download link that could possibly fix the issue if others want to experiment with it.
In addition, the original poster dgonreddit has a temporary fix as well that can make games "playable" at least. It is a lot shorter and simpler than Cranness, although it is still unclear which is more effective and if it universally applies to others.
Windows 8.1 was released last Thursday on October 17th. In light of the myriad of issues and bugs, the updates has been temporarily pulled from the Windows store.