#8 Splice (PS3, PS4, PC)
Moving the action to the scale of the petri dish, Splice is a puzzle game about bacteria. Each puzzle, or “sequence,” in the game has you start with a certain number of cells that you have to connect, split, and fuse in order to match a target diagram for an organism.
It’s delightfully tricky to predict the ways that the little cells will interact with each other, and the puzzles often center on thinking several moves ahead in order to successfully complete. Splice is also very nicely presented, with a modern minimalist UI, a slick microscopic look, and meditative ambient music.
