14. Q.U.B.E: Director's Cut
Nintendo never did get its own version of Portal, despite how well the non-violent 3D puzzler could have made use of the Wii Remote. Q.U.B.E. is obviously not Portal, but I think it could scratch that same itch — developed by the UK-based Toxic Games, Q.U.B.E. (Quick Understanding of Block Extrusion) drops you in a white, sterile environment that you must escape from through the power of physics and object manipulation. In this case, you have a special pair of gloves used to arrange colored blocks.
The original Q.U.B.E. was released for PCs back in 2011, followed by a Q.U.B.E: Director's Cut earlier this year, which will soon arrive on home consoles such as Wii U. The new version features new puzzles, of course, but it also has an entirely new soundtrack, a time trial mode, and a new story pumped up with voice acting.
However, anyone expecting the same kind of humor as in Portal shouldn't hold their breath — Q.U.B.E. is designed to be a far more serious experience.