5. Fallout
As we wrote in our previous list of best post-apocalyptic games, Fallout is the "big enchilada" of the whole genre. With six titles to its credit, and 5 of them actually good (we're discounting Fallout Tactics), it shows us the future as the 1950s imagined it and that we all did in fact drop the bomb.
The role-playing game series is not just about survival, but being able to move forward as a society. To rebuild in the aftermath of total annihilation, in the face of power hungry group, in the face of the repercussion of an unconscionable corporation, in the face of being lied to, in the face of running out of supplies. In the face of all this, you choose who you will be.