While we currently only know it by the placeholder title of "Zwei", Tango Gameworks, the studio founded by Resident Evil creator Shinji Mikami and owned by ZeniMax Media, has put up a teaser site with concept art for the title.
The art is meant to convey the feel for the game that the team is aiming to capture, but shouldn't be taken as a scene lifted directly therefrom.
Mikami has long been one of my very favorite designers and I've been wondering for a while what exactly Tango has been up to. Hopefully a final title and formal reveal for Zwei aren't too far off. TGS, maybe? I certainly hope so.