5. Victorian London
Why it'd be awesome:
Jack the Ripper, ridiculous Cockney accents, and steampunk gadgets, all set in one of the densest and most architecturally impressive cities in the world. Need we say any more?
Why it could happen:
If Florence, Rome, and Venice were the cultural centers of the Western world during the Renaissance, London undoubtedly held that banner for much of the 18th and 19th centuries. As the world's first true global superpower, the British Empire is perhaps the most logical next step for the franchise, and the urban sprawl of London would make an excellent game world.
Why it might not:
For as great as the geographic and cultural aesthetics would be, there just wasn't anything terribly important going on in 19th century London. The only real conflicts Britain experienced during the era were abroad, in its colonial ventures. Apart from the occasional crime spree, things were fairly quiet at home. It's just not likely that the Assassins would have had much to do, and we doubt Ubisoft is aching to include pipe smoking and tea sipping minigames. Maybe for the Kinect spinoff.