#6 Guild Wars 2
The term "WoW killer" has been bandied about so much by this point that's it's lost all meaning, but it's unquestionable that the timing is right for someone to dethrone Blizzard as the king of MMORPGs. World of Warcraft has been hemorrhaging subscribers for a while now, and while The Old Republic will likely fill the MMO void for some, those who prefer high fantasy will need another option. Enter Guild Wars 2. With one innovative (and very well received) MMO under their belt, developer ArenaNet seems poised to deliver the most revolutionary online RPG in recent memory.
What's most remarkable about Guild Wars 2 is that it essentially throws out all of the genre's established conventions. Everything from the basics of combat to leveling to PvP has its own unique flair. Even the quest system, the tried and true fallback of every MMO ever made, will be gone in Guild Wars 2, replaced with a dynamic event system and a storyline that responds to your actions. With any luck, we'll be searching for a Guild Wars 2 killer in a few years' time.