8. The Master (Fallout)
If you've never played the game, The Master is similar to that blob creature in the movie Slither. Before he turned into his hideous creature, The Master was actually a decent man trying to discover the origins of animal mutants that were attacking human survivors until he fell into a vat of F.E.V.
He eventually thought of a way to "unite" the wasteland by making everyone mutants, which I think was because of what happened to him. In the end, you can talk him out of it and he will commit suicide.