#8 Adam Jensen
The unwilling hero of Deus Ex Revolutions, Adam “I never asked for this” Jensen isn’t all that tragic to begin with, but if you’d start your story the way that Robocop begun his, you wouldn’t be that happy either. After having his body broken by a big augmented guy, Jensen is forced to get augmentations of his own. These aren’t easy to get used to though – you’re supposed to constantly take drugs to get the body to accept them, and they aren’t exactly comfy, plus I doubt you have an easy solution when you have a bad itch.
Eventually Adam accepts his augmentations or doesn’t, depending on your choices, but there ya go.