Seamstress Union (Shadowrun Returns)
Shadowrun is absolutely dripping in 80s cyberpunk theme, so it should be no surprise that your base of operation in Shadowrun Returns is a bar.
The Seamstress Union holds many quest-givers and NPCs, as well as an entire underground facility for shadowrunners willing to sell you black market weaponry and install augmented cyber enhancers. If it weren't for those pesky missions I'd never leave.