Witcher 3: Blood & Wine – DLC-Exclusive Mutations Guide

On PC, PS4 & Xbox One: Adapt to the new Toussaint region with these 12 Blood and Wine exclusive mutation upgrades, providing Geralt with powerful abilities not available in the main campaign.

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Adapt to the Duchy of Toussaint with new mutations in the Blood and Wine expansion to The Witcher 3: Wild Hunt. These powerful abilities provide Geralt special combat bonuses, like a buff that increases damage dependent on the number of enemies you’re facing, or one powerful skill that revives a downed Geralt with full health every three minutes.

Mutations come in three categories; combat, sign, and alchemy. Unlocking mutations costs a crafting material called mutagen, and always requires a pair of two ability points to research. These twelve character upgrades are only unlocked after completing a side quest available early in Blood and Wine. Learn all about mutations — how to unlock them and their bonus effects — with the full guide below.


DLC-Exclusive Mutations

Blood and Wine includes 12 new mutations. Mutations are ability upgrades that are unlocked through the use of mutagens and ability points.

  • How to Unlock Blood and Wine Mutagens:
    • Complete the Side Quest “Turn and Face the Strange”
    • This quest becomes available after completing the Main Quest “Blood Run”
    • While exploring the city of Beauclair in Toussaint, a messenger will deliver a letter to Geralt.
    • This unlocks the Side Quest and leads you to a cemetery that eventually reveals a Witcher researcher that is studying new mutations.

Complete these steps and the DLC-exclusive mutations will become available. Blood and Wine also pushes the level cap up to 100, so you should have plenty of chances to earn ability points and unlock these mutations.


Mutations List

Here you’ll find details on every type of mutation.

Bloodbath:

  • Mutation Type: Combat
  • Cost to Unlock: 2 Greater Red Mutagens / 2 Ability Points
  • Effect:
    • Gain +5% bonus damage per successful sword attack up to a maximum of +250%. All fatal blows dismember or trigger a finisher.

Magic Sensibilities:

  • Mutation Type: Sign
  • Cost to Unlock: 2 Greater Blue Mutagens / 2 Ability Points
  • Effect:
    • Sign abilities can now trigger critical hits. Chances of critical are improved with higher sign intensity unleashed. Enemies killed with a sign critical always explode.

Deadly Counter:

  • Mutation Type: Combat
  • Cost to Unlock: 2 Greater Red Mutagens / 2 Ability Points
  • Effect:
    • Sword attacks deal +25% damage to humans or monsters immune to counters. All enemies susceptible to counters will die instantly when countered with less than 25% health remaining.

Piercing Cold:

  • Mutation Type: Sign
  • Cost to Unlock: 2 Greater Blue Mutagens / 2 Ability Points
  • Effect:
    • Gain +25% chance of freezing enemy with Aard sign. If enemies are frozen while knocked down, they will shatter and die instantly. If not killed, enemies will sustain bonus damage.

Conductors of Magic:

  • Mutation Type: Combat / Sign
  • Cost to Unlock: 2 Greater Red Mutagens / 2 Ability Points
  • Effect:
    • Witcher / Unique / Magic swords increase sign damage by 50% of the equipped and drawn sword’s attack value.

Toxic Blood:

  • Mutation Type: Alchemy
  • Cost to Unlock: 2 Greater Green Mutagens / 2 Ability Points
  • Effect:
    • While Toxicity is at 0%, enemies receive 1.5% damage dealt to Geralt.

Euphoria:

  • Mutation Type: Alchemy
  • Cost to Unlock: 2 Greater Green Mutagens / 2 Ability Points
  • Effect:
    • Gain +0.75% to sword and sign damage for each of point of Toxicity, up to a maximum bonus of +75%.

Mutated Skin:

  • Mutation Type: Combat / Alchemy
  • Cost to Unlock: 2 Greater Red Mutagens / 2 Ability Points
  • Effect:
    • Gain -15% damage received for each full Adrenaline Point, up to a maximum of -45% damage.

Cat Eyes:

  • Mutation Type: Combat / Alchemy
  • Cost to Unlock: 2 Greater Red Mutagens / 2 Ability Points
  • Effect:
    • Gain +700% bonus to crossbow damage, and critical hit chances are increased to 50% odds. Crossbow bolts stun and knockdown enemies, and enemies with 100% of their health will lose 15% total vitality when hit with a bolt.

Adrenaline Rush:

  • Mutation Type: Combat / Sign
  • Cost to Unlock: 2 Greater Red Mutagens / 2 Ability Points
  • Effect:
    • +30% sword and sign damage per enemy faced for the first 30 seconds of combat. There is no cap for this bonus.
    • After the effects have worn off, Geralt’s sword and sign damage decrease by -10% per enemy faced for another thirty seconds. This debuff is capped at a -70% decrease in damage.

Metamorphosis:

  • Mutation Type: Check back soon for more info.
  • Cost to Unlock: Check back soon for more info.
  • Effect:
    • Landing a critical activates a random decoction effect for two minutes. This effect can be stacked to up to three simultaneous decoction effects active at once. This does not increase Toxicity level. Witcher Senses also now allow Geral to see in the dark.

Second Life:

  • Mutation Type: Check back soon for more info.
  • Cost to Unlock: Check back soon for more info.
  • Effect:
    • At 0% vitality, Geralt regenerates to 100% health and becomes temporarily invulnerable. This effect has a three-minute cooldown.

Fully explore the Duchy of Toussaint with every how-to and guide for Witcher 3: Blood & Wine on Gameranx:

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